A national vaccine safety collaboration

AEFI-CAN is a formal collaboration between Australian state and territory-based vaccine safety clinics involving adult and paediatric immunisation/infectious diseases/allergy specialists, representatives. It also includes representatives from the Therapeutic Goods Administration (TGA), most state/territory health departments and the Immunisation branch of the Australian Government Department of Health (DoH).

As a national network, AEFI-CAN works collaboratively to clinically assess and manage individual patients following serious or unexpected adverse events after immunisation. The network is also involved in developing a consistent robust national approach to serious and/or severe AEFI with the creation of standardised protocols; to standardise AEFI and clinical follow up reporting via the national AEFI-CAN database; to enhance community and health/vaccine provider knowledge and practice about AEFI and to provide expert advice to health professionals as required.

AEFI-CAN bridges the important link between surveillance and clinical assessment and management. As such, AEFI-CAN can assist in determining patient outcomes and support investigation of possible safety signals in a real-time integrated way.

The Victorian branch of AEFI-CAN is managed by SAEFVIC (Surveillance of Adverse Events Following Vaccination In the Community). SAEFVIC encourages online reporting of any adverse events following immunisation (AEFI) and are happy to be contacted regarding any vaccine safety query.


Authors: Adele Harris (SAEFVIC Research Nurse, Murdoch Children’s Research Institute) and Annette Alafaci (SAEFVIC Research Assistant, Murdoch Children’s Research Institute)

Date: April 2019

Materials in this section are updated as new information and vaccines become available. The Melbourne Vaccine Education Centre (MVEC) staff regularly reviews materials for accuracy.

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