{"id":22675,"date":"2026-03-17T16:38:06","date_gmt":"2026-03-17T05:38:06","guid":{"rendered":"https:\/\/mvec.mcri.edu.au\/?post_type=references&#038;p=22675"},"modified":"2026-03-26T16:20:21","modified_gmt":"2026-03-26T05:20:21","slug":"dengue","status":"publish","type":"references","link":"https:\/\/mvec.mcri.edu.au\/vi\/references\/dengue\/","title":{"rendered":"Dengue"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div data-parent=\"true\" class=\"vc_row row-container\" id=\"row-unique-0\"><div class=\"row single-top-padding single-bottom-padding one-h-padding full-width row-parent\"><div class=\"wpb_row row-inner\"><div class=\"wpb_column pos-top pos-center align_left column_parent col-lg-12 single-internal-gutter\"><div class=\"uncol style-light\"  ><div class=\"uncoltable\"><div class=\"uncell no-block-padding\" ><div class=\"uncont\" ><div class=\"uncode_text_column\" ><\/p>\n<h2><strong>C\u00fam l\u00e0 g\u00ec?<\/strong><\/h2>\n<p>Dengue, or dengue fever, is a viral illness caused by infection with the dengue virus (DENV).<\/p>\n<p>DENV is a single\u2011stranded RNA virus that, like <a href=\"https:\/\/mvec.mcri.edu.au\/references\/yellow-fever\/\">yellow fever virus<\/a> V\u00e0 <a href=\"https:\/\/mvec.mcri.edu.au\/references\/japanese-encephalitis\/\">Japanese encephalitis virus<\/a>, belongs to the genus <em>Flavivirus<\/em>. There are four serotypes of DENV. Immunity against one serotype does not provide protection against the other serotypes, meaning a person can experience dengue more than once in their lifetime. Severe disease is more likely with subsequent infections.<\/p>\n<h2><strong>C\u1ea7n \u0111\u1ec3 \u00fd nh\u1eefng g\u00ec<\/strong><\/h2>\n<p>Dengue has an incubation period of 3 to 14 days. Most people who are infected experience no symptoms or have mild symptoms which resolve in 1 to 2 weeks. Common symptoms include:<\/p>\n<ul>\n<li>high fever (40\u00b0C)<\/li>\n<li>severe headache<\/li>\n<li>muscle and joint pains<\/li>\n<li>ph\u00e1t ban<\/li>\n<li>pain behind the eyes<\/li>\n<li>abdominal pain, nausea and vomiting<\/li>\n<li>swollen glands.<\/li>\n<\/ul>\n<p>In rare cases, infection can progress to severe disease (dengue haemorrhagic fever, dengue shock syndrome) and display symptoms of severe abdominal pain, haematemesis (vomit with blood in it), tachypnoea (rapid breathing), bleeding from the gums or nose, fatigue, lethargy, pale and cold skin, or other unexplained bleeding. Severe dengue is a medical emergency.<\/p>\n<h2><strong>B\u1ec7nh l\u00e2y truy\u1ec1n qua \u0111\u01b0\u1eddng n\u00e0o<\/strong><\/h2>\n<p>DENV is primarily transmitted to humans via mosquitoes. Humans who are symptomatic can transmit the virus 2 days prior to symptom onset until 2 days after the fever has resolved. Asymptomatic cases (without symptoms) are also infectious. In rare cases, DENV can be transmitted through mucous membranes, blood transfusions, needle stick injuries and organ transplants. Maternal transmission during pregnancy (from mother to infant) has been reported and is <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7778400\/\" target=\"_blank\" rel=\"noopener\">linked<\/a> to pre\u2011term birth, low birthweight and post\u2011partum haemorrhage (severe bleeding).<\/p>\n<h2>D\u1ecbch t\u1ec5 h\u1ecdc<\/h2>\n<p>Dengue is now endemic in more than 100 countries across tropical and sub\u2011tropical areas in the Pacific, Asia, Africa and the Americas. There were 14.6 million cases of dengue reported to the World Health Organization (WHO) in 2024.<\/p>\n<p>DENV is not routinely found in Australia although imported cases (where a person is infected overseas) do occur. Mosquitoes capable of carrying dengue can be found in central and northern Queensland, the Northern Territory, northern Western Australia, and the Torres Strait. Local outbreaks of dengue, although rare, have historically occurred in northern Queensland and the Torres Strait.<\/p>\n<h2><strong>Ph\u00f2ng ng\u1eeba<\/strong><\/h2>\n<h3>R\u00e0o c\u1ea3n v\u1eadt l\u00fd<\/h3>\n<p>The mosquitoes capable of carrying dengue are active during the day. Care should be taken to avoid exposure by:<\/p>\n<ul>\n<li>m\u1eb7c qu\u1ea7n \u00e1o d\u00e0i, r\u1ed9ng r\u00e3i khi \u1edf ngo\u00e0i tr\u1eddi<\/li>\n<li>s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng mu\u1ed7i c\u00f3 ch\u1ee9a picaridin ho\u1eb7c DEET<\/li>\n<li>h\u1ea1n ch\u1ebf ho\u1ea1t \u0111\u1ed9ng ngo\u00e0i tr\u1eddi n\u1ebfu c\u00f3 nhi\u1ec1u mu\u1ed7i<\/li>\n<li>using fly sprays, mosquito coils and plug\u2011in repellent devices<\/li>\n<li>sleeping under mosquito nets treated with insecticides if sleeping indoors where windows, doors and vents are not covered by insect\u2011proof mesh (flywire screens), or if sleeping outdoors in an untreated tent or in the open.<\/li>\n<\/ul>\n<h3>Vaccination<\/h3>\n<p>Dengvaxia is a <a href=\"https:\/\/mvec.mcri.edu.au\/references\/vaccine-platforms\/\">live\u2011attenuated<\/a> recombinant tetravalent vaccine used for the prevention of <strong><div id=\"space\"><\/div><\/strong> dengue infections only. It is given as a 3\u2011dose course, with 6 months between each dose, and is suitable only where the all following conditions are met:<\/p>\n<ul>\n<li>Aged 9\u201345 years<br \/>\n<em>V\u00e0<\/em><\/li>\n<li>Previously infected with DENV<br \/>\n<em>V\u00e0<\/em><\/li>\n<li>Intending to reside in highly <span class=\"NormalTextRun SCXW12124413 BCX0\">dengue<\/span><span class=\"LastReplacedFindHitThemed SCXW12124413 BCX0\"><div id=\"space\"><\/div><\/span><span class=\"NormalTextRun SCXW12124413 BCX0\">endemic regions for extended periods<br \/>\n<em>V\u00e0<\/em><br \/>\n<\/span><\/li>\n<li>The potential benefits of vaccination outweigh the risks.<\/li>\n<\/ul>\n<p>It is only available through the <a href=\"https:\/\/www.tga.gov.au\/products\/unapproved-therapeutic-goods\/prescribe-unapproved-therapeutic-good-health-practitioners\/unapproved-products-individual-patients-special-access-scheme\" target=\"_blank\" rel=\"noopener\">Special Access Scheme (SAS)<\/a>, on a case\u2011by\u2011case basis, through specific application to the Therapeutic Goods Administration (TGA).<\/p>\n<h2>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba<\/h2>\n<p>Dengvaxia is not safe for people who have never been infected with DENV before. Given approximately <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10559824\/#:~:text=The%20factsheet%20about%20dengue%20of,are%20asymptomatic%E2%80%9D%20%5B8%5D.\" target=\"_blank\" rel=\"noopener\">40 to 80% of dengue infections are asymptomatic<\/a>\u00a0and there is no blood test sensitive enough to adequately confirm previous immunity, identifying who can safely be vaccinated is challenging.<\/p>\n<p>Dengvaxia has been linked to <a href=\"https:\/\/mvec.mcri.edu.au\/references\/vaccine-associated-enhanced-disease-vaed\/\">vaccine-associated enhanced disease (VAED)<\/a>, a rare phenomenon where a person who has been vaccinated experiences a (usually) more severe clinical presentation of an infection than would normally be seen in an unvaccinated person.<\/p>\n<p>It is a live-attenuated vaccine and therefore must not be given during <a href=\"https:\/\/mvec.mcri.edu.au\/references\/maternal-vaccination-during-pregnancy\/\">thai k\u1ef3<\/a> or to <a href=\"https:\/\/mvec.mcri.edu.au\/references\/immunosuppression-and-vaccines\/\">immunosuppressed<\/a> individuals.<\/p>\n<\/div><div class=\"uncode_text_column\" ><\/p>\n<h2>T\u00e0i li\u1ec7u<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dengue-and-severe-dengue\" target=\"_blank\" rel=\"noopener\">World Health Organization: Dengue<\/a><\/li>\n<li><a href=\"https:\/\/www.cdc.gov.au\/resources\/publications\/cdna-national-guidelines-dengue\" target=\"_blank\" rel=\"noopener\">Australian Centre for Disease Control: Dengue \u2013 CDNA National Guidelines for Public Health Units<\/a><\/li>\n<li><a href=\"https:\/\/www.health.gov.au\/resources\/publications\/atagi-advice-on-the-use-of-dengvaxiar-for-australians?language=en\" target=\"_blank\" rel=\"noopener\">ATAGI advice on the use of Dengvaxia for Australians<\/a><\/li>\n<li><a href=\"https:\/\/www.health.vic.gov.au\/infectious-diseases\/dengue-virus-disease\" target=\"_blank\" rel=\"noopener\">Victorian Department of Health: Dengue virus disease<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/dengvaxia\" target=\"_blank\" rel=\"noopener\">European Medicines Agency: Dengvaxia<\/a><\/li>\n<li><a href=\"https:\/\/www.cdc.gov.au\/diseases\/dengue\" target=\"_blank\" rel=\"noopener\">Australian Centre for Disease Control: Dengue<\/a><\/li>\n<\/ul>\n<p>\n<\/div><div class=\"uncode_text_column\" ><\/p>\n<div class=\"reviewedSection\">\n<p><strong>C\u00e1c t\u00e1c gi\u1ea3: <\/strong>Katie Butler (MVEC Education Nurse)<\/p>\n<p><strong>\u0110\u01b0\u1ee3cxem x\u00e9t b\u1edfi:\u00a0<\/strong>Rachael McGuire (MVEC Education Nurse Coordinator) and <span class=\"TextRun SCXW123785877 BCX0\" lang=\"EN-AU\" xml:lang=\"EN-AU\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW123785877 BCX0\">Linny Phuong (Paediatric Infectious Diseases Physician, MCRI)<\/span><\/span><\/p>\n<p><strong>Ng\u00e0y:<\/strong> March 2026<\/p>\n<p>T\u00e0i li\u1ec7u trong ph\u1ea7n n\u00e0y \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt khi c\u00f3 th\u00f4ng tin m\u1edbi v\u00e0 c\u00f3 v\u1eafc-xin. Nh\u00e2n vi\u00ean c\u1ee7a Trung T\u00e2m Gi\u00e1o D\u1ee5c V\u1eafc-xin Melbourne (MVEC) th\u01b0\u1eddng xuy\u00ean xem x\u00e9t \u0111\u1ed9 ch\u00ednh x\u00e1c c\u1ee7a c\u00e1c t\u00e0i li\u1ec7u.<\/p>\n<p>Qu\u00fd v\u1ecb kh\u00f4ng n\u00ean coi th\u00f4ng tin t\u1ea1i trang m\u1ea1ng n\u00e0y l\u00e0 l\u1eddi khuy\u00ean y t\u1ebf chuy\u00ean nghi\u1ec7p, c\u1ee5 th\u1ec3 cho s\u1ee9c kh\u1ecfe c\u1ee7a ri\u00eang m\u00ecnh ho\u1eb7c s\u1ee9c kh\u1ecfe ri\u00eang c\u1ee7a gia \u0111\u00ecnh qu\u00fd v\u1ecb. \u0110\u1ed1i v\u1edbi nh\u1eefng m\u1ed1i lo ng\u1ea1i v\u1ec1 y t\u1ebf, bao g\u1ed3m c\u00e1c quy\u1ebft \u0111\u1ecbnh v\u1ec1 ch\u1ee7ng ng\u1eeba, thu\u1ed1c men v\u00e0 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c, qu\u00fd v\u1ecb ph\u1ea3i lu\u00f4n h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/p>\n<\/div>\n<h6><\/h6>\n<p>\n<\/div><\/div><\/div><\/div><\/div><\/div><script id=\"script-row-unique-0\" data-row=\"script-row-unique-0\" type=\"text\/javascript\" class=\"vc_controls\">UNCODE.initRow(document.getElementById(\"row-unique-0\"));<\/script><\/div><\/div><\/div>\n<\/div>","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":"","_wp_rev_ctl_limit":""},"first_letter":[12],"class_list":["post-22675","references","type-references","status-publish","hentry","first_letter-d"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - 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