What is gelatin

Gelatin is a protein product derived from collagen. It is added to some vaccines to act as a stabiliser to ensure they remain effective after manufacture. The type of gelatin used in vaccines (usually porcine in origin) is different from the gelatin used in foods (usually bovine in origin) and is highly purified.

Gelatin allergy

The incidence of anaphylaxis to gelatin is extremely low. Some individuals with an allergy to gelatin will react to the ingestion of gelatin. Others react only when a vaccine containing gelatin is injected or with the use of intraoperative hemostatic agents (e.g. surgical Gelfoam®).

Gelatin and vaccines

Gelatin in vaccines can cause allergic reactions therefore people with severe allergies to gelatin should avoid gelatin-containing vaccines.

Patients who report allergic reactions to the ingestion of gelatin should seek expert advice before receiving any vaccine containing gelatin.

Vaccines licensed in Australia which contain gelatin (porcine)

  • MMRII® (measles-mumps-rubella)
  • ProQuad® (measles-mumps-rubella-varicella)
  • Varivax® (varicella)
  • Zostavax® (varicella-zoster)
  • Rabavert® (rabies)
  • Merieux® (rabies)
  • Vivotif® (typhoid)

If you have any concerns regarding a gelatin allergy and immunisation, please discuss with a healthcare professional or immunisation specialist.


作者: Adele Harris (SAEFVIC Research Nurse, Murdoch Children’s Research Institute), Nigel Crawford (Director, SAEFVIC, Murdoch Children’s Research Institute), Kirsten Perrett (Clinician Scientist Fellow, Murdoch Children’s Research Institute) & Nicole Wong (Immunisation Fellow, Royal Children’s Hospital)

审核人: Rachael McGuire(默多克儿童研究所 SAEFVIC 研究护士)

日期: 2020 年 7 月