{"id":1653,"date":"2016-11-28T10:42:26","date_gmt":"2016-11-28T09:42:26","guid":{"rendered":"http:\/\/www.mvec.vic.edu.au\/?page_id=1653"},"modified":"2023-10-05T12:25:36","modified_gmt":"2023-10-05T01:25:36","slug":"mthfr-gene","status":"publish","type":"references","link":"https:\/\/mvec.mcri.edu.au\/zh\/references\/mthfr-gene\/","title":{"rendered":"MTHFR gene"},"content":{"rendered":"
<\/p>\n

Background<\/span><\/h2>\n

M<\/span>ethylenetetrahydrofolate reductase (MTHFR) <\/span>is an enzyme<\/span> that<\/span> helps the body<\/span> to break<\/span> down <\/span>folate<\/span>.<\/span> The <\/span>MTHFR enzyme is<\/span> made<\/span> by <\/span>the <\/span>MTHFR <\/span>gene<\/span>. <\/span>Harmless changes in the <\/span>MTHFR gene<\/span>,<\/span> polymorphisms<\/span>,<\/span> are <\/span>very common<\/span>. <\/span>Importantly, <\/span>MTHFR <\/span>polymorphisms do <\/span>not <\/span>cause<\/span> any significant<\/span> health problems. <\/span>MTHFR gene <\/span>variants or <\/span>mutations are different to gene polymorphisms<\/span> and <\/span>are <\/span>very rare<\/span>.<\/span> For more information about the MTHFR gene, refer to the resource below [Resources:<\/span> VCGS MTHFR<\/span>]<\/span>.<\/span><\/span><\/p>\n

MTHFR gene polymorphisms and vaccines<\/span><\/h2>\n

People who have MTHFR gene polymorphisms can safely receive vaccines. There is no increased risk of adverse events following immunisation (AEFI).<\/span><\/p>\n

MTHFR gene polymorphism testing<\/span><\/h2>\n

There is no clinical indication for MTHFR polymorphism testing before vaccination.<\/span><\/p>\n<\/div>

<\/p>\n

Resources<\/span><\/b><\/h2>\n