背景
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that helps the body to break down folate. 这 MTHFR enzyme is made by 这 MTHFR gene. Harmless changes in the MTHFR gene, polymorphisms, 是 very common. Importantly, MTHFR polymorphisms do 不是 原因 any significant health problems. MTHFR gene variants or mutations are different to gene polymorphisms 和 是 very rare. For more information about the MTHFR gene, refer to the resource below [Resources: VCGS MTHFR].
MTHFR gene polymorphisms and vaccines
People who have MTHFR gene polymorphisms can safely receive vaccines. There is no increased risk of adverse events following immunisation (AEFI).
MTHFR gene polymorphism testing
There is no clinical indication for MTHFR polymorphism testing before vaccination.
作者： Nigel Crawford（默多克儿童研究所 SAEFVIC 主任）和 Margie Danchin（默多克儿童研究所高级研究员）
Reviewed by: Katie Butler (MVEC Education Nurse Coordinator) 和 Sally Gordon (MVEC Senior Research Fellow)
日期： October 2023
本章节内的材料将随着新信息和新疫苗的出现而进行更新。墨尔本疫苗教育中心（MVEC）职员定期审阅材料的准确性。
You should not consider the information on this site to be specific, professional medical advice for your personal health or for your family’s personal health. For medical concerns, including decisions about vaccinations, medications and other treatments, you should always consult a healthcare professional.