आयु: हम टीके के रोलआउट में देरी नहीं कर सकते हैं और सर्दियों में बड़ी बीमारी का जोखिम उठा सकते हैं

कई वैज्ञानिकों द्वारा प्रस्तावित COVID-19 वैक्सीन रोलआउट को रोकने का आह्वान चिंता का कारण है।

The following article suggests that Australia's initial public health goal should be a rapid vaccine rollout and not herd immunity, in order to limit further risk of major illness. In order to achieve a rapid rollout, both the AstraZeneca and Pfizer COVID-19 vaccines are needed. Recent modelling suggests that vaccination will most likely shift SARS-CoV-2 from a virus causing major disease burden, to a relatively benign coronavirus causing the common cold.

लेख को पूरा पढ़ने के लिए नीचे दिए गए लिंक का अनुसरण करें:

आयु: हम टीके के रोलआउट में देरी नहीं कर सकते हैं और सर्दियों में बड़ी बीमारी का जोखिम उठा सकते हैं


शिखर निकाय ऑस्ट्रेलिया की COVID-19 वैक्सीन रणनीति का समर्थन करते हैं

13 जनवरी, 2020 को जारी एक बयान में, द संक्रामक रोगों के लिए आस्ट्रेलियाई समाज (एएसआईडी), द ऑस्ट्रेलियन कॉलेज फॉर इंफेक्शन प्रिवेंशन एंड कंट्रोल (एसीआईपीसी) और यह पब्लिक हेल्थ एसोसिएशन ऑफ़ ऑस्ट्रेलिया (PHAA) have shown support for the Commonwealth Government's COVID-19 vaccine strategy. The statement suggests that recent media reports surrounding concerns for the ability of any vaccine to create herd immunity is unjustified and reinforces that the public should have confidence in the approach being taken to provide COVID-19 vaccines to Australians.

बयान को पूरा पढ़ने के लिए नीचे दिए गए लिंक पर क्लिक करें:

शिखर निकाय ऑस्ट्रेलिया की COVID-19 वैक्सीन रणनीति का समर्थन करते हैं


बच्चों का नेटवर्क बढ़ाना - नए टीकाकरण संसाधन

MVEC के साथ भागीदारी की है बच्चों का नेटवर्क बढ़ाना माता-पिता केंद्रित टीकाकरण संसाधनों को विकसित करने के लिए टीका प्रतिरक्षा और टीका विकास प्रक्रिया को समझाएं।

इन लेखों को देखने के लिए नीचे दिए गए लिंक का अनुसरण करें:

टीका विकास: परिवारों के लिए एक गाइड

वैक्सीन इम्युनिटी: टीके संक्रामक रोगों को कैसे रोकते हैं

 


Zostavax vaccine: Safety advisory - risk of disseminated varicella zoster virus (vaccine strain) infection

Following a third report of fatal disseminated vaccine strain varicella-zoster virus infection following Zostavax administration, the Therapeutic Goods Administration (TGA) is reminding health professionals that Zostavax should not be used in people with compromised immune function.

Further details on the alert can be seen here:

Zostavax vaccine: Safety advisory

For more information on Zostavax® and access to the Zostavax® GP decision aid please review the MVEC pages below:

एमवीईसी: दाद

एमवीईसी: Zoster vaccine (Zostavax®) FAQ’s


FDA report reveals phase 3 clinical trial data for the Moderna COVID-19 vaccine candidate

In preparation for a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC), the FDA has made public the interim results of phase 3 clinical trials for the Moderna COVID-19 vaccine candidate. This meeting will discuss the Emergency Use Authorisation (EUA) application and determine any recommendations for approval.

Phase 3 clinical trials for this vaccine were spread across 99 sites in the United States and participants were aged 18 years or older. The Moderna vaccine utilises a messenger RNA (mRNA) platform. Interim results show an acceptable safety profile. Following the administration of 2 doses, 28 days apart, it is reported that this vaccine has an efficacy rate of 94.5%.

To read the document in full please refer to the link below:

Vaccines and Related Biological Products Advisory Committee: FDA briefing document- Moderna COVID-19 vaccine


The Conversation: How did the University of Queensland/CSL vaccine fail due to 'false positive' HIV tests? A vaccine expert explains

Further clinical trials of the UQ/CSL COVID-19 vaccine candidate have been called off after phase 1 results showed that participants had returned 'false positive' HIV tests. The UQ/CSL vaccine utilises molecular clamp technology involving components of a HIV protein. These components are unable to cause a HIV infection, however participants were shown to be creating antibodies against HIV which then leads to a false positive HIV test result.

The following article confirms that no safety concerns had been identified. It suggests that researchers acted appropriately to limit unnecessary anxiety over inaccurate test results and to reinforce public confidence in a future COVID-19 vaccine program.

लेख को पूरा पढ़ने के लिए नीचे दिए गए लिंक का अनुसरण करें:

The Conversation: How did the University of Queensland/CSL vaccine fail due to 'false positive' HIV tests? A vaccine expert explains


The Conversation: People with severe allergies warned off Pfizer COVID vaccine for now. But that may change as more details emerge

As a precautionary measure, the UK medicines regulator have advised that people with a significant history of allergic reactions should not receive the Pfizer/BioNTech COVID-19 vaccine after 2 people experienced allergic reactions. The following article outlines how common allergies to vaccines are, why these types of reactions weren't noted in clinical trials and the role of ongoing safety surveillance and monitoring.

लेख को पूरा पढ़ने के लिए नीचे दिए गए लिंक का अनुसरण करें:

The Conversation: People with severe allergies warned off Pfizer COVID vaccine for now. But that may change as more details emerge 

 

 


Australian Government Department of Health: COVID-19 vaccines

The Australian Government Department of Health have developed a dedicated resource for COVID-19 vaccines. This site will host news and information for Australians about the development, approval process and plans for COVID-19 vaccines.

To access this resource, please follow the link below:

Australian Government Department of Health: COVID-19 vaccines


FDA report reveals phase 3 clinical trial data for the Pfizer and BioNTech COVID-19 vaccine candidate

In preparation for a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC), the FDA has made public the interim results of phase 3 clinical trials for the Pfizer and BioNTech COVID-19 vaccine candidate. This meeting will discuss the Emergency Use Authorisation (EUA) application and determine any recommendations for approval.

Phase 3 clinical trials were spread across the US, Argentina, Brazil, Germany, South Africa and Turkey. The Pfizer and BioNTech vaccine candidate utilises a messenger RNA (mRNA) platform and its' studies involved participants aged 16 to  85 years. Findings have shown that the vaccine candidate has an acceptable safety profile and following the administration of 2 doses, has an efficacy rate of 95%.

To read the document in full please refer to the link below:

Vaccines and Related Biological Products Advisory Committee: FDA briefing document- Pfizer-BioNTech COVID-19 vaccine


The Lancet: Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa and the UK

The Oxford Vaccine Trial group have published interim results for phase 3 clinical trials of their COVID-19 vaccine candidate (ChAdOx1 vCoV-19). This vaccine utilises a viral vector platform and previous phase 1/2 studies have shown an acceptable safety profile. Participants in the phase 3 trials, held across the UK, Brazil and South Africa, were aged 18y or older. Findings have shown that when participants received 2 equal doses, vaccine efficacy was 62.1%. Participants who received a lower dose followed by a standard dose, vaccine efficacy was 90.0%.

To read the article and view these results in full, follow the link below:

The Lancet: Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa and the UK