Discoloured leg syndrome

पृष्ठभूमि

Discoloured leg syndrome (DLS) is a rare phenomenon that कर सकना occur after receipt of an injected vaccine. It is a transient condition involv

Diagnosis

DLS है be diagnosed based on clinical presentation (e.g. symptom profile, onset of symptoms and symptom resolution).

Unlike injection site reactions (ISRs), DLS does not radiate from the site of injection, and can impact one or both legएस, even if only one injection has been administered. Discolouration can also extend up to the pelvis.

Investigations are generally not required. Despite the presence of petechiae, there is no drop in platelet count.

As DLS involves skin changes and symptoms can occur quickly, it is important to differentiate it from anaphylaxis, especially if symptoms start within 30 minutes of vaccination.

Association and incidence

DLS is reported at a rate of 58 per 100,000 children vaccinated. Although the median onset time for colour change is approximately 3.5 hours, DLS can be seen quite quickly post-vaccination (within 30 minutes). Where symptoms of petechiae occur, the median onset time is 12 hours following vaccination. Generally, colour change (median duration = approximately 2 hours) does not last as long as petechiae (median duration = 54 hours).

इलाज

As a precaution, assessment of airway, breathing and circulation is advised.

Symptoms of DLS are transient and will resolve on their own without treatment.

Any adverse event following immunisation (AEFI), including DLS, should be reported to the adverse event reporting service in your jurisdiction. In Victoria, this is सैफविक.

भविष्य की खुराक के लिए निहितार्थ

Recurrence of DLS है uncommon, but can occur. एचowever, DLS है not a contraindication to receiving future vaccines. Given that DLS appears to be age-related, families can be reassured that children are less likely to experience symपीtoms as they get older.

संसाधन

• Finnish Institute for Health and Welfare: Swelling in a lower limb and changes in skin colour after a vaccination
• Kemmeren JM, Vermeer-de Bondt PE, van der Maas NA. Discolored leg syndrome after vaccination–descriptive epidemiology. Eur जे Pediatr. 2009;168(1):43-50. doi:10.1007/s00431-008-0707-0