The Australian Technical Advisory Group on Immunisation (ATAGI) has released clinical guidance on the use of a different COVID-19 vaccine as the second dose.

The advice recommends to use the same COVID-19 vaccine for the 2 doses of the primary vaccination course, unless there are specific medical reasons not to do so, or the same vaccine brand is not available in Australia.

The ATAGI advice explains:
• The medical contraindications and serious vaccine-attributable adverse events after
dose 1 of a COVID-19 vaccine that warrant using an alternative vaccine brand for dose 2
• The medical conditions that mean that Comirnaty is recommended over COVID-19
Vaccine AstraZeneca
• The recommendations for completing the primary vaccination course for people who
have received dose 1 with a vaccine that is not available in Australia.

To read the statement in full, please click the link below:
ATAGI statement: ATAGI clinical advice on use of a different COVID-19 vaccine as the second dose in special circumstances

For further information on COVID-19 mixed vaccine schedules refer to MVEC: COVID-19 mixed vaccine schedules.