Mpox (monkeypox) is a viral zoonosis (an infection spread from animals to humans) caused by a virus that belongs to the Orthopoxvirus genus (which also causes the variola virus responsible for smallpox disease and the vaccinia virus, which is used in smallpox vaccines). Since the eradication of smallpox in 1980, mpox has become the most important orthopoxvirus affecting humans, however, causes less severe disease than smallpox.

Increasing numbers of Mpox have been reported globally over the last 2 years, with 141 confirmed or probable cases identified in Australia as of November 2022. Vaccination is currently recommended for individuals identified at highest risk of exposure and severe disease.

Our immunisation reference page has recently been updated to include:

  • intradermal administration recommendations
  • changes in terminology for pre-exposure and post-exposure prophylaxis.

To view the updated page in full, refer to the link below:

MVEC: Mpox (monkeypox)