Monkeypox is a viral zoonosis (an infection spread from animals to humans). It is caused by a virus that belongs to the Orthopoxvirus genus (which also causes the variola virus responsible for smallpox disease and the vaccinia virus, which is used in smallpox vaccines). 

Historically, smallpox vaccines have been used in the prevention of smallpox infection, however, they are also likely to be effective against monkeypox. 

There are two types of smallpox vaccines available for use in Australia for the prevention of monkeypox: 

  • ACAM2000™ – 2nd generation, live-attenuated vaccine 
  • JYNNEOS® – 3rd generation, non-replicating vaccine 

Our Monkeypox reference page has been updated to included expanded eligibility criteria for those at highest risk of being infected.  

To view the updated page in full, follow the link below: 

MVEC: Monkeypox

MVEC acknowledges the traditional owners of the lands on which we live, work and educate. We pay our respects to their Elders, past, present and emerging.
We are committed to honouring Australian Aboriginal and Torres Strait Islander peoples’ unique cultural and spiritual relationships to the land, waters and seas.

About MVEC

The Melbourne Vaccine Education Centre (MVEC) is an educational website, developed with the aim of providing up-to-date immunisation information for both healthcare professionals and members of the public. We are based at Murdoch Children’s Research Institute (MCRI), a research organisation, and are affiliated with SAEFVIC (Surveillance of Adverse Events Following Vaccination in the Community), the Victorian Vaccine Safety Service.

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