Mpox (monkeypox) is a viral zoonosis (an infection spread from animals to humans) caused by a virus that belongs to the Orthopoxvirus genus (which also causes the variola virus responsible for smallpox disease and the vaccinia virus, which is used in smallpox vaccines). Since the eradication of smallpox in 1980, mpox has become the most important orthopoxvirus affecting humans, however, causes less severe disease than smallpox.

Increasing numbers of Mpox have been reported globally over the last 2 years, with 141 confirmed or probable cases identified in Australia as of November 2022. Vaccination is currently recommended for individuals identified at highest risk of exposure and severe disease.

Our immunisation reference page has recently been updated to include:

  • intradermal administration recommendations
  • changes in terminology for pre-exposure and post-exposure prophylaxis.

To view the updated page in full, refer to the link below:

MVEC: Mpox (monkeypox)

MVEC acknowledges the traditional owners of the lands on which we live, work and educate. We pay our respects to their Elders, past, present and emerging.
We are committed to honouring Australian Aboriginal and Torres Strait Islander peoples’ unique cultural and spiritual relationships to the land, waters and seas.

About MVEC

The Melbourne Vaccine Education Centre (MVEC) is an educational website, developed with the aim of providing up-to-date immunisation information for both healthcare professionals and members of the public. We are based at Murdoch Children’s Research Institute (MCRI), a research organisation, and are affiliated with SAEFVIC (Surveillance of Adverse Events Following Vaccination in the Community), the Victorian Vaccine Safety Service.

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