Researchers at Monash Health have published findings related to vocal cord dysfunction/inducible laryngeal obstruction(s) (VCD/ILO) in relation to incident-associated VCD which may be related to vaccination.

Their findings are related to a case series of ten individuals who were initially labelled as having experienced anaphylaxis following COVID-19 vaccination. These individuals were referred on to a specialist allergy service, where 9 out of the 10 received a second dose of the same COVID-19 vaccine that caused their initial reaction.  It was found that 2 out of the 10 individuals met the Brighton Criteria for anaphylaxis, and symptoms recurred in 8 of the 9 individuals who received a second dose, mirroring their initial reactions which had been diagnosed as anaphylaxis.

Clinical features of VCD/ILO overlap with those of the Brighton Criteria for vaccine-related anaphylaxis, with this research demonstrating the need for providers to be able to differentiate between anaphylaxis and VCD/ILO.

To read the article in full, please follow the link below:

过敏和临床免疫学杂志:声带功能障碍/诱导性喉阻塞模仿 SARS-CoV-2 (COVID-19) 疫苗接种期间的过敏反应

For further information on how to differentiate between anaphylaxis and an acute stress response, refer to the animation on the MVEC:过敏和免疫 reference page.