美国医学协会称，由于冠状病毒封锁期间病例数大幅下降，流感死亡得以避免

ABC 报道的新数据表明，在 COVID-19 大流行期间实施的社交距离措施、减少旅行和其他限制似乎导致流感病例数量急剧下降。 

澳大利亚医学协会的克里斯·莫伊博士谨慎地指出，我们实际上可能推迟了流感的爆发，但仍然相信流感病例的数量将会减少，因为今年我们的免疫人口要多得多。 

在这里阅读更多内容： 

美国广播公司（ABC）：美国医学协会称，随着冠状病毒封锁期间病例数大幅下降，流感死亡得以避免 

MVEC 团队强烈支持接种疫苗作为预防季节性流感的一种方式，请阅读我们的更多信息 MVEC 流感疫苗建议. 

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COVID19 疫苗之路播客第 3 集：Andrew Pollard 教授

在“新冠肺炎疫苗之路”系列的第三集中，我们的主持人 Nigel Crawford 副教授将与牛津大学儿科感染与免疫学教授 Andrew Pollard 教授进行对话。 Pollard 教授是牛津疫苗小组的负责人，该小组与詹纳研究所一起正在进行牛津 COVID-19 疫苗试验。
 
他们将讨论：
 
  • 牛津疫苗中心的 COVID-19 疫苗试验由牛津疫苗集团和詹纳研究所进行，波拉德教授是共同领导者 
  • 牛津疫苗集团之前在中东呼吸综合征 (MERS) 冠状病毒疫苗方面的工作如何使他们能够使用同一平台快速开始 SARS-2 疫苗的工作
  • 先前对 MERS 和 SARS 疫苗的研究如何深入了解冠状病毒的生物学和可能的保护性抗原
  • 疫苗开发中的疫苗安全问题，如抗体增强性疾病 (AED) 以及疫苗安全在试验设计和评估中的重要作用
  • 牛津疫苗中心目前 ChAdOx1 nCoV-19 疫苗试验的最新进展
  • 随机试验中对照组的使用以及 COVID-19 牛津疫苗试验如何在对照组中使用脑膜炎球菌疫苗 
  • 社区疾病减少导致传播率降低和曲线变平如何影响疫苗试验设计和研究地点的位置
  • 大流行所需的疫苗生产规模扩大，以及在疫苗可用时在全球范围内公平获取疫苗的重要性
资源：
 
 
您可以通过我们的 播客页面 或通过以下链接：
 
 

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COVID19 Road to a vaccine episode 2: Professor Kathryn Edwards

In episode 2 of our ‘COVID19 Road to a vaccine series’, Associate Professor Nigel Crawford, from the Murdoch Children’s Research Institute (MCRI), Melbourne, Australia, speaks with Professor Kathryn Edwards. Dr Edwards is a professor of paediatrics in the division of infectious diseases at Vanderbilt University School of Medicine in Nashville, Tennessee, where she is also vice-chair for clinical research. She is an internationally-recognised expert in vaccinology and, in particular, vaccine safety. 
 
They will be discussing the important topic of vaccine safety when developing a new vaccine, including some of the challenges faced in the COVID19 vaccine development pathway.
 
在这一集中，他们讨论了：
 
  • Professor Edwards' perspective on vaccine safety across her roles as a clinician/scientist/researcher
  • Adverse events following immunisation and their implications when developing new vaccines
  • Vaccine safety across the different phases (I to IV) of clinical trials
  • The importance of data safety and monitoring committees in vaccine trials
  • What we can learn from the historical research into the development of SARS and MERS vaccines
  • What is ADE (antibody-dependent enhancement of virus infection) and why is it an important consideration in COVID19 vaccine development?
  • What are adjuvants and how does the use of them affect safety planning?
  • Should pregnant women and children be involved in vaccine trials and how can their participation be managed safely?
  • The importance of transparency and honest communication with the public in regards to vaccine safety

You can listen to the episode via our 播客页面 或通过以下链接：

喇叭 - 苹果 - Spotify 音乐 

经过 艾丽丝·布莱克

COVID19 Road to a vaccine episode 1: Professor Stanley Plotkin

In Episode 1 of our new podcast series, Associate Professor Nigel Crawford, a vaccinologist and consultant paediatrician at the Murdoch Children’s Research Institute (MCRI) & Royal Children’s Hospital (RCH), Melbourne, talks with Stanley Plotkin, Emeritus Professor of Paediatrics at the University of Pennsylvania; who is well known internationally for his role in vaccine development.

在这一集中，他们讨论了：

  • Professor Plotkin’s role in the development of the rubella vaccine, still used throughout the world today
  • His role as the Editor in Chief of the ‘Vaccines’ textbook
  • His role in the formation of the Coalition for Epidemic Preparedness and Innovation (CEPI) and CEPI’s current role in global COVID-19 vaccine development
  • What can we learn from the H1N1 pandemic in the development of a COVID-19 vaccine?
  • How developing a vaccine against coronaviruses is critical to the future of civilisation as economies are being destroyed by these viruses
  • Human challenge models and some of the ethical considerations we need to tackle if these sorts of trials are going to be undertaken to support COVID-19 vaccine development
  • Success can only be achieved through global collaboration in the pursuit of a COVID-19 vaccine
  • How the practical aspects of distributing a vaccine on this scale have never been faced before and the importance of thinking outside the box!

资源：

在这里收听该片段：

喇叭 - Apple Podcasts - Spotify Podcasts 

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Special MVEC podcast series: COVID19 Road to a vaccine

The year 2020 has seen the emergence of the SARS-CoV-2 virus (COVID19), a unique and potentially devastating virus, with no known prevention or treatment. This new SARS-2 virus has shown to not only have significant international health implications, but also immense psychological and economic impacts. Associate Professor Nigel Crawford, a vaccinologist and consultant paediatrician at the Murdoch Children’s Research Institute (MCRI) & Royal Children’s Hospital (RCH), Melbourne, will delve into the global pursuit of a safe and effective vaccine to prevent COVID19. This is all occurring at ‘pandemic speed’ and MVEC’s new podcast will explore this complicated and multi-faceted process through interviews with a variety of national and international vaccine experts.

In our first few episodes, we will be talking with vaccine experts Emeritus Professor Stanley Plotkin, Professor Kathryn Edwards and Professor Andrew Pollard. 

Listen via our 播客页面 or subscribe below on your preferred podcast platform:

喇叭 - Apple podcasts - Spotify podcasts 

经过 艾丽丝·布莱克

COVID-19 大流行期间维持免疫服务的 ATAGI 指导原则

Immunisation remains an essential service during the COVID-19 pandemic and it is very important immunisation providers maintain routine immunisation services whilst complying with measures to reduce the risk of transmission of COVID-19.

If scheduled vaccines are missed or delayed and the overall vaccination coverage rates drop, the risk of a resurgence of a well-controlled vaccine preventable disease like measles is increased. If this happens during or after the current pandemic, it places further stress on the health care system.

With this  in mind, ATAGI (Australian Technical Advisory Group on Immunisation) have released guiding principles on maintaining immunisation services during the COVID-19 pandemic:

ATAGI: Guiding principles for maintaining immunisation services during the COVID-19 pandemic

经过 艾丽丝·布莱克

新播客：Covid-19 和儿童，由 Nigel Crawford 副教授主讲

Nigel Crawford 副教授在 Healthed Australia 的 Going Viral 播客中接受全科医生兼 RACGP 主席 Harry Nespolon 博士的采访。他们讨论了 COVID-19 和儿童，涵盖以下内容：

  • 儿童是超级传播者、无症状传播者吗？
  • 学校和家庭的传播——我们知道什么？
  • 发烧的孩子 – 我应该怀疑 COVID-19 吗？
  • 育儿注意事项
  • 流感合并感染和疫苗接种
  • 新生儿和垂直传播

您可以在这里收听播客：

健康澳大利亚：病毒式传播第 27 集：儿童、新生儿和传播；育儿考虑；流感合并感染和疫苗接种

经过 艾丽丝·布莱克

针对 COVID-19 的卡介苗疫苗临床试验 (BRACE)

在 Nigel Curtis 教授的领导下，默多克儿童研究所的研究人员正在进行一项针对 COVID-19 的 BCG 疫苗的随机对照临床试验。这项名为 BRACE 试验（卡介苗接种以减少澳大利亚医护人员接触冠状病毒后感染 COVID-19 的影响）的研究已得到世界卫生组织总干事谭德塞 (Tedros Adhanom Ghebreyesus) 的认可。

卡介苗 (BCG) 疫苗旨在提供预防结核病的保护，也可能提供免疫力以预防其他感染。 BRACE 试验的目的是调查 BCG 疫苗接种是否可以预防医护人员感染 COVID-19 或减轻其症状的严重程度。

这导致了人们 不要 符合寻求接种 BCG 疫苗的试验标准。

MVEC和医师BCG专家就这个问题达成了共识，具体如下：

我们强烈建议任何人不要在临床试验之外使用卡介苗，除非他们符合标准 澳大利亚免疫手册结核病指南.

众所周知，卡介苗可以有效保护幼儿免受结核病的侵害，但近年来却受到全球短缺的影响。使用未经证实的疫苗（如卡介苗）会给接种者和处方者带来风险。此外，在试验之外额外使用卡介苗疫苗可能会导致需要该疫苗来预防结核病的婴儿短缺。由于目前海外旅行受到限制，许多提供卡介苗的旅行诊所已被暂停。然而，当旅行限制（包括前往结核病流行国家）取消时，旅行和医院卡介苗诊所将致力于增加疫苗的使用机会。

授权人：

  • Nigel Curtis 博士、Nigel Crawford 博士、Jim Buttery 博士、Shidan Tosif 博士、Daryl Cheng 博士和 Teresa Lazzaro 博士
    -2020 年 4 月 8 日

资源：

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Telethon Kids 为家长、家庭和学校提供 COVID-19 资源

Telethon Kids Institute 为家长、家庭和学校创建了资源，其中专家提供最新建议并解决社区问题（包括社区孩子们的视频问答环节）。 

他们的信息可靠、最新，并且基于现有的最佳证据。

您可以在以下位置查看他们的资源：

儿童电视马拉松：COVID-19

经过 艾丽丝·布莱克