ATAGI: Statement on the clinical use of Arexvy
ATAGI (Australian Technical Advisory Group on Immunisation) has published a statement on the clinical use of Arexvy, a respiratory syncytial virus (RSV) vaccine, for the prevention of RSV in older adults in Australia.
Respiratory syncytial virus (RSV) is one of the leading causes of respiratory tract infections in young children and is associated with severe respiratory disease in people aged over 60 years.
Arexvy is available on the private market, and is recommended for:
- all adults aged over 75 years
- First Nations Australians aged 60 to 74 years
- Non-Indigenous Australians with medical conditions that increase their risk of severe disease due to RSV.
ATAGI’s full statement includes further details on recommendations, contraindications, coadministration, RSV and Arexvy.
A new chapter on RSV will be available in the Australian Immunisation Handbook by mid-2024. Until then, use the ATAGI statement for clinical guidance.
ATAGI: Statement on the clinical use of Arexvy
CDC on RSV vaccine administration errors
The CDC reports that, in the United States, the respiratory syncytial virus (RSV) vaccine Arexvy has been administered in error to some children and pregnant people. Arexvy is not approved for use in infants or young children, or pregnant people. Most of the reported administration errors occurred in outpatient settings (e.g. GP clinics and pharmacies).
In January Arexvy was registered by the Therapeutic Goods Administration (TGA) for use in Australia, for the immunisation of people aged 60 years and older to prevent lower respiratory tract disease caused by RSV.
ATAGI (Australian Technical Advisory Group on Immunisation) today (29 February 2024) published guidance on the clinical use of Arexvy.
New MVEC podcast: The Vaccine Coverage
MVEC is excited to share that we will be launching a brand new podcast series: The Vaccine Coverage.
This podcast series will feature conversations with special guests on a range of topics relating to vaccination in Australia. The Vaccine Coverage is for anyone who wants to learn more about vaccination: parents, individuals receiving vaccines and vaccine providers too.
Stay tuned.
And in the meantime, check out our previous podcast series COVID19 Đường đến vắc-xin, in which MVEC Director Prof Nigel Crawford interviewed national and international vaccine experts in the leadup to the launch of COVID-19 vaccines.
Immunisation Coalition: 2024 Meningococcal webinar
The Immunisation Coalition will host the 2024 Meningococcal webinar on Tuesday 20 February.
The webinar will provide an update on invasive meningococcal disease (IMD) in the community, and features Prof Robert Booy with Dr Andrew Baird as moderator.
When: 6:00 pm EDT on 20 February 2024
Learn more about the webinar and register through the Immunisation Coalition.
WHO: Nearly 10 000 children vaccinated as malaria vaccine rollout in Africa expands
Nearly 10,000 children in Burkina Faso and Cameroon have received the RTS,S malaria vaccine in recent weeks. The vaccine rollout in the two countries is a critical step forward in the fight against one of the leading causes of death in Africa. At least 28 African countries plan to introduce a malaria vaccine as part of their national immunisation programs.
There have been two malaria vaccines endorsed for use in Africa: RTS,S (available now) and R21 (expected to be available in mid 2024). Four doses are recommended for both vaccines; 3 by 9 months of age and the last dose at 18 months of age.
WHO: Nearly 10 000 children vaccinated as malaria vaccine rollout in Africa expands
Gavi: Vaccine profiles: malaria
The Guardian: Brazil starts mass vaccination amid upsurge in dengue fever
Brazil has become the first country to roll out a national dengue vaccination program, in response to a surge of dengue fever cases across the country. The country's health ministry said nearly 365,000 dengue cases were reported in the first five weeks of 2024, four times the number during the same period in 2023.
Brazil has purchased 5.2m doses of the dengue vaccine Qdenga and is commencing vaccination of children aged 10 to 14 years.
Dengue is a viral infection, spread by mosquitoes to people. Since the beginning of 2023, there have been more than five million cases globally and more than 5,000 dengue-related deaths reported.
The Guardian: Brazil starts mass vaccination amid upsurge in dengue fever
WHO: Disease outbreak news: Dengue
MCRI: Study into rare side effects of COVID-19 vaccines
A new international study will examine the rare side effects caused by COVID-19 vaccines.
The University of Alberta in Canada is leading the study, through the Mạng lưới Dịch vụ Chủng ngừa Đặc biệt Quốc tế (INSIS). INSIS brings together specialist clinicians in vaccine safety, systems biology and genomics, including AusVaxAn toàn, to characterise the risk factors and underlying mechanism of adverse events following COVID-19 immunisation.
INSIS focuses on very rare adverse reactions, those which affect less than 0.001 % of the population, that occur after COVID-19 vaccination. This study aims to understand the causes and risk factors behind these occurrences, to ensure the development of even safer vaccines in potential future pandemics.
Read more on the Murdoch Children’s Research Institute (MCRI) website.
MVEC: Mạng lưới Dịch vụ Chủng ngừa Đặc biệt Quốc tế
MVEC: AusVaxSafety: giám sát an toàn vắc-xin tại Úc
MVEC: AEFI-CAN: Adverse Events Following Immunisation – Clinical Assessment Network
New immunisation reference page: Open disclosure
Open disclosure is an accreditation requirement of all health services under the National Safety and Quality Health Service (NSQHS) Standards. Open disclosure should occur after any vaccine error, and includes a discussion with the affected person, or their families, carers or other support persons. Open disclosure can be challenging and complex. However, it can produce benefits such as improved transparency and communication between clinicians and patients; and opportunities for health services to improve care delivery systems and processes.
MVEC has recently published a new immunisation reference page on Open disclosure.
New home for COVID-19 information
Coronavirus (COVID-19) Victoria has now moved all COVID-19 information to a new home on the Better Health Channel. Check the website for consumer and clinician information on disease prevention, testing, treatment, long covid, and special risk group advice.
Better Health: Coronavirus (COVID-19) Victoria
Cases of measles rising around the world
Rates of measles have been rising around the world. There were 127 cases in the United Kingdom in January 2024, leading the UK Health Security Agency to declare a National Incident.
In Australia, there were 5 confirmed measles cases in January 2024. This includes 3 in Victoria, 1 in ACT and 1 in Queensland.
The World Health Organization (WHO) reported a 30-fold increase in measles cases across Europe from 2022 to 2023.
These data remind us of the importance of achieving and maintaining over 95% coverage with 2 doses of measles-containing vaccine.